Synthesis of a quaternary polyprenyl ammonium salt.
نویسندگان
چکیده
Reaction of primary C(55)-allylic alcohol moraprenol (WT(3)C(7-9)-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies.
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ورودعنوان ژورنال:
- Acta biochimica Polonica
دوره 54 4 شماره
صفحات -
تاریخ انتشار 2007